Pfungwa yebundu
Bundu chipenyu chitsva chinoumbwa nekuwanda kusingaite kwemasero emumuviri, ayo anowanzo ratidza seabnormal tissue mass (bundu) munzvimbo yenzvimbo yemuviri. Kuumbwa kwebundu mhedzisiro yekusagadzikana kwakakomba kwesero kukura mutemo pasi pekuita kweakasiyana tumorigenic zvinhu. Kuwedzera kusingaite kwemasero kunokonzeresa kuumbwa kwebundu kunonzi neoplastic proliferation.
Muna 2019, Cancer Cell yakaburitsa chinyorwa nguva pfupi yadarika. Vatsvagiri vakaona kuti metformin inogona kumisa zvakanyanya kukura kwebundu mukutsanya, uye vakakurudzira kuti PP2A-GSK3β-MCL-1 nzira inogona kunge iri chinangwa chitsva chekurapa bundu.
Musiyano mukuru pakati pebenign bundu uye rinouraya bundu
Benign bundu: kunonoka kukura, capsule, kuzvimba kukura, kutsvedza kusvika pakubata, muganhu wakajeka, hapana metastasis, kazhinji fungidziro yakanaka, zviratidzo zvekumanikidzwa kwenzvimbo, kazhinji hapana muviri wese, kazhinji hazvikonzere kufa kwevarwere.
Bundu rinokuvadza (kenza): kukurumidza kukura, kukurumidza kukura, kunamatira kune zvinyama zvakapoteredza, kusakwanisa kufamba kana kubatwa, muganhu usina kujeka, metastasis iri nyore, nyore kudzokorora mushure mekurapa, kuderera kwefivha, kusava nehanya kwekudya mukutanga kwekutanga, kuderedza uremu, kupera kwakanyanya, kupererwa neropa uye fever munguva yekupedzisira, nezvimwewo. Kana isina kurapwa munguva, inowanzotungamirira kurufu.
"Nemhaka yekuti zvipembenene zvinotapira uye zvipembenene zvakashata hazvina kungova nezviratidzo zvakasiyana-siyana zvemakiriniki, asi zvinonyanya kukosha, kufungidzira kwavo kwakasiyana, saka kana iwe uchinge wawana bundu mumuviri wako uye zviratidzo zviri pamusoro, unofanira kutsvaga mazano ekurapa munguva."
Individualized kurapwa kwebundu
Human Genome Project uye International Cancer Genome Project
Human Genome Project, iyo yakavambwa zviri pamutemo muUnited States muna 1990, ine chinangwa chekuvhura macode ese emajini angangosvika zviuru zana mumuviri wemunhu uye kudhirowa huwandu hwemajini evanhu.
Muna 2006, International Cancer Genome Project, yakatangwa pamwe chete nenyika dzakawanda, imwe tsvakiridzo huru yesainzi mushure meHuman Genome Project.
Matambudziko makuru mukurapwa kwebundu
Individualized diagnosis uye kurapwa = Individualized diagnosis + targeted zvinodhaka
Kune varwere vazhinji vakasiyana vanorwara nechirwere chimwe chete, nzira yekurapa ndeye kushandisa mushonga mumwechete uye mwero weyero, asi kutaura zvazviri, varwere vakasiyana vane misiyano mikuru mukurapa uye maitiro akashata, uye dzimwe nguva musiyano uyu unotouraya.
Targeted drug therapy ine hunhu hwekusarudzika kuuraya kwebundu maseru pasina kuuraya kana kungokuvadza masero akajairwa, ane madiki mhedzisiro, ayo anovandudza hupenyu uye kurapa kwevarwere.
Nekuti kurapa kwakanangwa kwakagadzirirwa kurwisa chaiwo mamorekuru anonangwa, zvinodikanwa kuona bundu majini uye kuona kana varwere vaine zvinangwa zvinoenderana vasati vatora zvinodhaka, kuitira kuti vakwanise kurapa.
Kuonekwa kwetumor gene
Tumor gene yekuona inzira yekuongorora uye kuteedzera iyo DNA/RNA yemamota maseru.
Kukosha kwekuonekwa kwebundu gene kutungamira kusarudzwa kwemishonga yekurapa zvinodhaka (mishonga yakanangwa, immune checkpoint inhibitors uye imwe AIDS itsva, kurapwa kunonoka), uye kufanotaura fungidziro nekudzokazve.
Mhinduro dzakapihwa neAcer Macro & Micro-Test
Human EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR）
Inoshandiswa pakuonekwa kwemhando yezvakajairwa shanduko mu exon 18-21 yeEGFR gene muvanhu vasiri diki cell kenza yemapapu varwere in vitro.
1. Kuunzwa kwemukati wekutarisa kunaka kwekutonga muhurongwa kunogona kunyatso tarisa maitiro ekuyedza uye kuve nechokwadi chekuyedza mhando.
2. Kunzwa kwakanyanya: chiyero chekuchinja che1% chinogona kuonekwa zvakasimba kumashure kwe3ng / μL wild-type nucleic acid reaction solution.
3. High specificity: hapana kuchinjika kunosangana nemhedzisiro yekuona yesango-rudzi rwemunhu genomic DNA uye mamwe marudzi anochinja.
KRAS 8 Mutation Detection Kit (Fluorescence PCR)
Mhando sere dzekuchinja kwemakodoni 12 uye 13 eK-ras gene anoshandiswa kutarisisa hunhu hweDNA yakatorwa kubva muparafini yemunhu-embedded pathological section in vitro.
1. Kuunzwa kwemukati wekutarisa kunaka kwekutonga muhurongwa kunogona kunyatso tarisa maitiro ekuyedza uye kuve nechokwadi chekuyedza mhando.
2. Kunzwa kwakanyanya: chiyero chekuchinja che1% chinogona kuonekwa zvakasimba kumashure kwe3ng / μL wild-type nucleic acid reaction solution.
3. High specificity: hapana kuchinjika kunosangana nemhedzisiro yekuona yesango-rudzi rwemunhu genomic DNA uye mamwe marudzi anochinja.
Munhu ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Inoshandiswa kuona zvine mutsindo gumi nemana emhando dzeROS1 fusion gene muvanhu vasiri diki cell cancer yemapapu varwere in vitro.
1. Kuunzwa kwemukati wekutarisa kunaka kwekutonga muhurongwa kunogona kunyatso tarisa maitiro ekuyedza uye kuve nechokwadi chekuyedza mhando.
2. High senitivity: 20 makopi e fusion mutation.
3. High specificity: hapana kuchinjika kunosangana nemhedzisiro yekuona yesango-rudzi rwemunhu genomic DNA uye mamwe marudzi anochinja.
Munhu EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Inoshandiswa kuona 12 mutation mhando dzeEML4-ALK fusion gene muvanhu vasiri diki cell cancer cancer varwere in vitro.
1. Kuunzwa kwemukati wekutarisa kunaka kwekutonga muhurongwa kunogona kunyatso tarisa maitiro ekuyedza uye kuve nechokwadi chekuyedza mhando.
2. High senitivity: 20 makopi e fusion mutation.
3. High specificity: hapana kuchinjika kunosangana nemhedzisiro yekuona yesango-rudzi rwemunhu genomic DNA uye mamwe marudzi anochinja.
Munhu BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR)
Inoshandiswa kuona zvine hunyanzvi shanduko yeBRAF gene V600E muparafini-yakamisikidzwa tishu samples dze melanoma yemunhu, colorectal cancer, thyroid cancer uye yemapapu in vitro.
1. Kuunzwa kwemukati wekutarisa kunaka kwekutonga muhurongwa kunogona kunyatso tarisa maitiro ekuyedza uye kuve nechokwadi chekuyedza mhando.
2. Kunzwa kwakanyanya: chiyero chekuchinja che1% chinogona kuonekwa zvakasimba kumashure kwe3ng / μL wild-type nucleic acid reaction solution.
3. High specificity: hapana kuchinjika kunosangana nemhedzisiro yekuona yesango-rudzi rwemunhu genomic DNA uye mamwe marudzi anochinja.
| Chinhu Nha | Product Name | Tsanangudzo |
| HWTS-TM006 | Munhu EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 bvunzo/kiti 50 bvunzo/kiti |
| HWTS-TM007 | Munhu BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR) | 24 bvunzo/kiti 48 bvunzo/kiti |
| HWTS-TM009 | Munhu ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 bvunzo/kiti 50 bvunzo/kiti |
| HWTS-TM012 | Human EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR） | 16 bvunzo/kiti 32 bvunzo/kiti |
| HWTS-TM014 | KRAS 8 Mutation Detection Kit (Fluorescence PCR) | 24 bvunzo/kiti 48 bvunzo/kiti |
| HWTS-TM016 | Munhu TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 bvunzo/kiti |
| HWTS-GE010 | Munhu BCR-ABL Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 bvunzo/kiti |
Nguva yekutumira: Kubvumbi-17-2024