Pfungwa yegomarara
Bundu chinhu chitsva chinoumbwa nekuwanda kwemasero mumuviri, izvo zvinowanzoonekwa sebundu risina kujairika (bundu) mumuviri. Kuumbwa kwebundu kunokonzerwa nekusagadzikana kukuru kwekukura kwemasero pasi pechiito chezvinhu zvakasiyana-siyana zvinokonzera bundu. Kuwanda kwemasero kusina kujairika kunotungamira mukuumbwa kwebundu kunonzi neoplastic proliferation.
Muna 2019, Cancer Cell yakaburitsa chinyorwa munguva pfupi yapfuura. Vaongorori vakaona kuti metformin inogona kudzivirira kukura kwegomarara zvakanyanya kana munhu achitsanya, uye vakaratidza kuti nzira yePP2A-GSK3β-MCL-1 ingave iri chinangwa chitsva chekurapa gomarara.
Musiyano mukuru pakati pegomarara risina njodzi negomarara rakaipa
Bundu risina njodzi: kukura zvishoma nezvishoma, kapusule, kukura kwekuzvimba, kutsvedza kusvika pakubata, muganhu wakajeka, hapana metastasis, kazhinji fungidziro yakanaka, zviratidzo zvekumanikidzwa kwenzvimbo, kazhinji hapana muviri wese, kazhinji hazvikonzeri rufu rwevarwere.
Gomarara rinouraya (gomarara): kukura nekukurumidza, kukura kunopinda mumuviri, kunamira kune nyama dzakapoteredza, kutadza kufamba kana wabatwa, muganhu usina kujeka, kupararira kuri nyore, kudzoka kuri nyore mushure mekurapwa, fivha shoma, kushaya chido chekudya pakutanga, kudzikira kwehuremu, kupera simba zvakanyanya, kupererwa neropa uye fivha pakupera kwechikamu, nezvimwewo. Kana ikasarapwa nenguva, inowanzokonzera rufu.
"Nekuti bundu risina njodzi nemabundu akaipa hazvina zviratidzo zvakasiyana zvekiriniki chete, asi chinonyanya kukosha ndechekuti fungidziro yaro yakasiyana, saka kana wangowana bundu mumuviri wako nezviratidzo zvataurwa pamusoro apa, unofanira kutsvaga rubatsiro rwechiremba nenguva."
Kurapa bundu nenzira yemunhu oga
Chirongwa cheGenome yeVanhu neChirongwa cheGenome yeKenza chePasirose
Chirongwa cheHuman Genome Project, chakatangwa zviri pamutemo muUnited States muna 1990, chine chinangwa chekuvhura makodhi ese emajini angangoita 100,000 mumuviri wemunhu uye kudhirowa huwandu hwemajini evanhu.
Muna 2006, International Cancer Genome Project, yakatangwa pamwe chete nenyika dzakawanda, ndeimwe tsvakurudzo huru yesainzi mushure meHuman Genome Project.
Matambudziko makuru mukurapa bundu
Kuongororwa kwemunhu mumwe nemumwe uye kurapwa = Kuongororwa kwemunhu mumwe nemumwe + mishonga yakanangana nayo
Kune varwere vazhinji vanorwara nechirwere chimwe chete, nzira yekurapa ndeyekushandisa mushonga mumwe chete uye chiyero chakajairika, asi kutaura chokwadi, varwere vakasiyana vane mutsauko mukuru mumhedzisiro yekurapa uye maitiro asina kunaka, uye dzimwe nguva mutsauko uyu unotouraya.
Kurapa nemishonga yakanangana kune hunhu hwekuuraya masero egomarara nenzira yakasarudzika pasina kuuraya kana kungokuvadza masero akajairwa kashoma, nemhedzisiro diki, izvo zvinovandudza hupenyu hwevarwere uye mhedzisiro yekurapa.
Nekuti kurapa kwakanangana kwakagadzirirwa kurwisa mamorekuru chaiwo, zvakakosha kuona majini egomarara uye kuona kana varwere vane zvinangwa zvinoenderana nazvo vasati vatora mishonga, kuitira kuti ishandise simba rayo rekurapa.
Kuonekwa kwemajini ebundu
Kuona majini egomarara inzira yekuongorora nekutevera DNA/RNA yemasero egomarara.
Kukosha kwekuona majini egomarara kutungamira kusarudzwa kwemishonga yekurapa (mishonga inonangwa, mishonga inodzivirira immune checkpoint nezvimwe zvitsva zveAIDS, kurapwa kunonoka), uye kufanotaura kufambira mberi kwechirwere uye kudzoka kwacho.
Mhinduro dzakapihwa neAcer Macro & Micro-Test
Kiti yeKuona Kuchinja kweGene 29 yeHuman EGFR (Fluorescence PCR)）
Inoshandiswa pakuona mafambiro emuviri (qualitatively) ekuchinja kwakajairika mu exon 18-21 yejini reEGFR muvarwere vekenza yemapapu vasiri masero madiki muvanhu.
1. Kuunzwa kwekutonga kwemhando yepamusoro mukati mehurongwa kunogona kutarisa zvizere maitiro ekuyedza uye kuve nechokwadi chemhando yekuyedza.
2. Kunzwa kwakanyanya: mwero wekuchinja kwe1% unogona kuonekwa zvakanaka mushure me3ng/μL wild-type nucleic acid reaction solution.
3. Kunyatsojeka: hapana kusangana kwemhedzisiro yekuona DNA ye genomic yemunhu yemhando yemusango nedzimwe mhando dze mutant.
Kiti yeKRAS 8 Mutations Detection Kit (Fluorescence PCR)
Mhando sere dzekuchinja kwemajini mumakodhoni 12 ne13 eK-ras dzinoshandiswa pakutsvaga DNA yakatorwa kubva muzvikamu zvezvirwere zvakaiswa parafini muvanhu mu vitro.
1. Kuunzwa kwekutonga kwemhando yepamusoro mukati mehurongwa kunogona kutarisa zvizere maitiro ekuyedza uye kuve nechokwadi chemhando yekuyedza.
2. Kunzwa kwakanyanya: mwero wekuchinja kwe1% unogona kuonekwa zvakanaka mushure me3ng/μL wild-type nucleic acid reaction solution.
3. Kunyatsojeka: hapana kusangana kwemhedzisiro yekuona DNA ye genomic yemunhu yemhando yemusango nedzimwe mhando dze mutant.
Kiti yeKuona Kuchinja Kwemajini eROS1 yeHuman ROS1 (Fluorescence PCR)
Inoshandiswa kuona mhando gumi nemana dzekuchinja kweROS1 fusion gene muvanhu vasiri masero madiki ekenza yemapapu mu vitro.
1. Kuunzwa kwekutonga kwemhando yepamusoro mukati mehurongwa kunogona kutarisa zvizere maitiro ekuyedza uye kuve nechokwadi chemhando yekuyedza.
2. Kunzwa kwakanyanya: makopi makumi maviri ekuchinja kwefusion.
3. Kunyatsojeka: hapana kusangana kwemhedzisiro yekuona DNA ye genomic yemunhu yemhando yemusango nedzimwe mhando dze mutant.
Kiti yeKuona Kuchinja Kwemajini EML4-ALK yeHuman EML4-ALK (Fluorescence PCR)
Inoshandiswa kuona mhando gumi nembiri dzekuchinja kweEML4-ALK fusion gene muvanhu vasiri masero madiki ekenza yemapapu mu vitro.
1. Kuunzwa kwekutonga kwemhando yepamusoro mukati mehurongwa kunogona kutarisa zvizere maitiro ekuyedza uye kuve nechokwadi chemhando yekuyedza.
2. Kunzwa kwakanyanya: makopi makumi maviri ekuchinja kwefusion.
3. Kunyatsojeka: hapana kusangana kwemhedzisiro yekuona DNA ye genomic yemunhu yemhando yemusango nedzimwe mhando dze mutant.
Kiti yeKuona Mutation yeBRAF Gene V600E yeMunhu (Fluorescence PCR)
Inoshandiswa kuona kushanduka kweBRAF gene V600E mumasampuli enyama akaiswa paraffin e melanoma yemunhu, kenza ye colorectal, kenza ye thyroid uye kenza yemapapu mu vitro.
1. Kuunzwa kwekutonga kwemhando yepamusoro mukati mehurongwa kunogona kutarisa zvizere maitiro ekuyedza uye kuve nechokwadi chemhando yekuyedza.
2. Kunzwa kwakanyanya: mwero wekuchinja kwe1% unogona kuonekwa zvakanaka mushure me3ng/μL wild-type nucleic acid reaction solution.
3. Kunyatsojeka: hapana kusangana kwemhedzisiro yekuona DNA ye genomic yemunhu yemhando yemusango nedzimwe mhando dze mutant.
| Nhamba yechinhu | Zita rechigadzirwa | Tsanangudzo |
| HWTS-TM006 | Kiti yeKuona Kuchinja Kwemajini EML4-ALK yeHuman EML4-ALK (Fluorescence PCR) | bvunzo makumi maviri pakiti bvunzo makumi mashanu/kit |
| HWTS-TM007 | Kiti yeKuona Mutation yeBRAF Gene V600E yeMunhu (Fluorescence PCR) | bvunzo makumi maviri nemana/kit bvunzo makumi mana nemasere/kit |
| HWTS-TM009 | Kiti yeKuona Kuchinja Kwemajini eROS1 yeHuman ROS1 (Fluorescence PCR) | bvunzo makumi maviri pakiti bvunzo makumi mashanu/kit |
| HWTS-TM012 | Kiti yeKuona Kuchinja kweGene 29 yeHuman EGFR (Fluorescence PCR)） | bvunzo gumi nematanhatu/kit bvunzo makumi matatu nemaviri/kit |
| HWTS-TM014 | Kiti yeKRAS 8 Mutations Detection Kit (Fluorescence PCR) | bvunzo makumi maviri nemana/kit bvunzo makumi mana nemasere/kit |
| HWTS-TM016 | Kiti yeKuona Kuchinja Kwemajini eTelefoni yeHuman TEL-AML1 (Fluorescence PCR) | bvunzo makumi maviri nemana/kit |
| HWTS-GE010 | Kiti yeKuona Kuchinja Kwemajini eBCR-ABL yeHuman BCR-ABL (Fluorescence PCR) | bvunzo makumi maviri nemana/kit |
Nguva yekutumira: Kubvumbi-17-2024