Zvishandiso zveKuona Carbapenemases zveKucheka-Kumucheto

CRE, inoonekwa nenjodzi huru yekutapukirwa, kufa kwakanyanya, mitengo yakakwira uye kuomamukurapwa, zvinoda kuti pave nekuonekwa nekukurumidza, kwakanaka uye kwakaruramanzira dzekubatsira kuongororwa kwekiriniki uye kurapwa.

Sekureva kweStudy yemasangano makuru nezvipatara, Rapid Carbapenemases Detection Kit (Colloidal Gold) kubva kuMacro & Micro -Test, yakaenzana nemulti-qPCR assay, inopa kururama kwakakwana kwe100% mukuona carbapenemases muzvipembenene zvebhakitiriya. Kushanda uku kwakanaka kunopfuura nzira dzechinyakare dze phenotypic dzakadai semCIM/eCIM neCDT. Zvakakosha, colloidal gold assays inoratidza 100% sensitivity, specificity, positive predictive value, uye negative predictive value kune yega yega carbapenemase yakaedzwa, zvichiratidza kushanda kwayo kwakanaka uye kwakarongeka mukuona mabhakitiriya anogadzira carbapenemase.

Sarudzo 1:

KukurumidzaKiti Yekuona Carbapenemases (Colloidal Gold), kufambira mberi kwekupedzisira kugadzirisa dambudziko rekukurumidzira reCRE riri kutyisidzira hutano hweveruzhinji pasi rose, mazuva 1-2 pamberi penzira yekubatwa nezvinodhaka;

 Maminetsi gumi nemashanukungoziva NDM, KPC, OXA-48, IMP uye VIM mubvunzo mumwe chete;

 Kushanda kuri nyore nekushandisa mvura yekuongorora ropa pasina plate culture, maminetsi gumi chete ekuchenesa nekusuka;

 Kunzwa kwakanyanya uye kusaita zvinhu zvakasiyana-siyana nemabhakitiriya anowanzo konzera zvirwere akadai seKlebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa kana mamwe masampuli anogadzira β-lactamase;

 Kushanda Kwakakura: Mamiriro akasiyana-siyana anosanganisira zvipatara, makiriniki, nenzvimbo dzehutano dzemunharaunda.

Sarudzo yechipiri:

Kiti Yekuona Majini Anodzivirira Carbapenem (Fluorescence PCR), Bvunzo ye6-mu-1nemhedzisiro iri mukatiMaminetsi makumi mana, inonyatsoratidzaNDM, KPC, OXA23, OXA-48, IMP uye VIMmubvunzo imwe chete;

 Kutora Sample Zviri Nyore: Mapundu, swab yemudumbu kana kuti makoroni akachena;

 Mutengo Wakaderedzwa: Zvinangwa zvitanhatu zvakaonekwa nebvunzo imwe chete zvinodzivirira bvunzo dzisina kudzokororwa;

 Kunzwa Kwakanyanya & Kunyatsojeka: 1000CFU/mL yekuona kuti munhu anogona kubatwa sei uye kuti hapana kusangana kwezvirwere zvinotapukira kana kuti masampuli ane mamwe majini asingabatanidzwi nemishonga anonzi CTX, mecA, SME, SHV, TEM, nezvimwewo;

 Kuenderana Kwakakura: Nezvishandiso zvePCR;