Crucial bcr-abl kusaona kwe cml kurapwa

Chirwere chenguva isingaperi (cml) chirwere chakaipisisa chechirwere chegomatipoetic stem cell. Anopfuura 95% yeCML varwere vanotakura iyo Philadelphia chromosome (phi) mumasero eropa. Uye iyo bcr-abl fusion geno inoumbwa neyekupararira pakati peABL proto-Oncorye (ABLELON MUFANANIDZO 9 (9QTOTOL) of chromosome 22 (22q11). Its folusion proted neiyi gene ine tyrosine kinase (tk) chiitiko charo, pi3k) kusimudzira musero weapoptosis, kuita masero anowedzera zvinokuvadza, uye nekudaro zvichikonzera kuitika kwe cml.

BCR-AbL Fusion Genes, iyo yakakosha mukuvandudzwa kweCML, inoshanda sekiyi yekuongorora yekuongorora ye cml. Kuonekwa kwayo kunobatsira kuongorora murwere'SPindura kune tyrosine kinase inhibitors (tkis) uye inofanotaura lukemia kudzokorora, izvo zvakakosha pakubata kweCML murwere mpress manejimendi.

Hunhu Bcr-AblFusion gen mutation kuona kitkubva macro & micro-bvunzo yekukwana kuwanikwa kweBcr-abl mu cml varwere, anobatsira cml kuongororwa uye maGuides akaisa kiriniki kurapwa Kuti uwedzere kurongedza maratidziro ezvirongwa zvekushanda kwemurwere.CR-AbL Fusione, iyondizvozvakakoshaMukuvandudzwa kwe cml,inoshanda sekiyi yekuongororaofCml. Kuonekwa kwayo kunobatsiraTarisamurwere'sMhinduro kune Tyrosine Kinase Inhibitors (TKIS)uyefantts leukemia kudzokorora, irizvakakoshato zvinoshandaCmlMurwere Management.

Human Bcr-Abl Fusion gener mutation kuwanikwa kit kubva macro & micro-bvunzo yekukwana kuwanikwa kweBcr-abl mu cml varwere, anobatsiraCmlkuongororwauyeGuidesTargeted kurapwa kwekirinikitoOptimizemaratidziro ekurapa ekushanda kwemurwere ekudzivirira.

KuregererwaDEXCATE:Panguva imwe chetekuwanikwaNekuti3Common Fiusion maJaini (P210, P190, P230)Nekutikufukidzwa kukuru uyekudzivirira kubva pamatare ematare;

Kukwikwidza kwakanyanya:Iyo yemvura shanduro inoona majini ejinine lodyemakopi 1000 / ml,uye Shanduro yeiyo lyotofilizedof 500 makopi / ml;

ZvakanakaACCURACY: Inapesterkutongauye ung enzyme kudzivirira mapepa enhema&Negatives;

Kushanda kuri nyore uye kushanda zvakanaka:Yakavharwa-tube kushanda,isina zvigadzirwapost-kugadzirisa,uyekuwanikwamukatiMaminitsi makumi matanhatuNekutiChinangwa uye Zvakavimbika Mhedzisiro;

ZvimweSarudzo:Mvura uye lyepilized vhezheni dzezvisarudzo zvevatengi;

Kuwedzeredza Kuwedzeredza:Inoenderana neyakawandisa PCR masisitimu ekushanda kweLAB LABL