Kuramba kweMycobacterium Tuberculosis
Zita rechigadzirwa
HWTS-RT074A-Mycobacterium Tuberculosis Rifampicin Resistance Detection Kit (Fluorescence PCR)
Epidemiology
Rifampicin yave ichishandiswa zvakanyanya mukurapa varwere vane TB yemapapu kubvira kuma1970, uye ine mhedzisiro yakakosha. Yave iri sarudzo yekutanga yekupfupisa kurapwa kwechemotherapy kwevarwere vane TB yemapapu. Kusagona kweRifampicin kunonyanya kukonzerwa nekuchinja kwegene reRpoB. Kunyangwe mishonga mitsva yekurwisa TB ichiramba ichibuda, uye kushanda kwevarwere vane TB yemapapu kwakaramba kuchikwira, kuchine kushomeka kwemishonga yekurwisa TB, uye chiitiko chekushandisa mishonga isina musoro mukurapa chakakwira. Zviri pachena kuti Mycobacterium Tuberculosis muvarwere vane TB yemapapu hachigone kuurayiwa zvachose nenguva, izvo zvinozopedzisira zvaita kuti murwere arambe achiramba achirwara, zvichiita kuti chirwere chirambe chichienderera mberi, uye zvinowedzera njodzi yekufa kwemurwere. Kit iyi yakakodzera kuongororwa kweMycobacterium Tuberculosis uye kuonekwa kweRifampicin Resistance Gene, izvo zvinobatsira kunzwisisa kusagona kweMycobacterium Tuberculosis inobatwa nevarwere, uye kupa nzira dzekubatsira dzekurapa nhungamiro yemishonga.
Epidemiology
| Zita rechinangwa | Mutori wenhau | Mudzimisi | ||
| Reaction BufferA | Reaction BufferB | Reaction BufferC | ||
| rpoB 507-514 | rpoB 513-520 | IS6110 | FAM | Hapana |
| rpoB 520-527 | rpoB 527-533 | / | CY5 | Hapana |
| / | / | Kudzora kwemukati | HEX(VIC) | Hapana |
Magadzirirwo ehunyanzvi
| Kuchengetera | ≤-18℃ Murima |
| Nguva yekuzorora | mwedzi mipfumbamwe |
| Rudzi rwemuenzaniso | Masvoto |
| CV | 15% |
| LoD | mhando yemusango inodzivirira rifampicin: 2x103mabhakitiriya/mL homozygous mutant: 2x103mabhakitiriya/mL |
| Kunyatsojeka | Inoona mycobacterium tuberculosis yemusango uye nzvimbo dzekuchinja kwemamwe majini asingapindi mishonga akadai se katG 315G>C\A, InhA-15C>T, mhedzisiro yebvunzo hairatidzi kuramba rifampicin, zvinoreva kuti hapana kubatanidzwa kwemishonga. |
| Zvishandiso Zvinoshanda: | Masisitimu ePCR eSLAN-96P Munguva Yechokwadi (Hongshi Medical Technology Co., Ltd.) |
Kufamba Kwebasa
