Mycobacterium Tuberculosis Rifampicin Resistance
Product name
HWTS-RT074A-Mycobacterium Tuberculosis Rifampicin Resistance Detection Kit (Fluorescence PCR)
Epidemiology
Rifampicin yakashandiswa zvakanyanya mukurapa varwere vepulmonary tuberculosis kubva mukupera kwema1970, uye ine simba rakakura.Yakave sarudzo yekutanga kupfupisa chemotherapy yevarwere vepulmonary tuberculosis.Kuramba kweRifampicin kunonyanya kukonzerwa nekushandurwa kwejene rerpoB.Kunyange zvazvo mishonga mitsva yekurwisa tibhii iri kuramba ichibuda, uye kushanda kwekiriniki kwevarwere vepulmonary tuberculosis kwakaramba kuchiwedzera, kuchine kushaikwa kwemishonga inorwisa tibhii, uye chiitiko chekushandisa zvinodhaka zvisina musoro mumakiriniki zvakanyanyisa.Zviri pachena kuti Mycobacterium tuberculosis muvarwere vane pulmonary tuberculosis haigoni kuurayiwa zvachose panguva yakakodzera, iyo inoguma inotungamirira kumadhigirii akasiyana-siyana ekudzivirira zvinodhaka mumuviri wemurwere, inowedzera nguva yechirwere, uye inowedzera ngozi yekufa kwemurwere.Kiti iyi yakakodzera kuongororwa kwechirwere cheMycobacterium tuberculosis pamwe nekuonekwa kwerifampicin resistance gene, zvinobatsira kunzwisisa kusamira zvakanaka kwemishonga yemycobacterium tuberculosis inobatwa nevarwere, uye nekupa dzimwe nzira dzekubatsira pakurapwa kwemishonga.
Epidemiology
Zita rechinangwa | Reporter | Quencher | ||
Reaction BufferA | Reaction BufferB | Reaction BufferC | ||
rpoB 507-514 | rpoB 513-520 | IS6110 | FAM | Hapana |
rpoB 520-527 | rpoB 527-533 | / | CY5 | Hapana |
/ | / | Kudzora mukati | HEX(VIC) | Hapana |
Technical Parameters
Storage | ≤-18℃ Murima |
Sherufu-hupenyu | 9 mwedzi |
Type Type | Sputum |
CV | <5% |
LoD | rifampicin-resistant mhando yemusango: 2x103utachiona/mL homozygous mutant: 2x103utachiona/mL |
Zvakananga | Inoona mhuka yemusango mycobacterium tuberculosis uye nzvimbo dzekuchinja kwemamwe majini ekuramba zvinodhaka akadai se katG 315G>C\A, InhA-15C>T, mibairo yebvunzo inoratidza kusaramba rifampicin, zvinoreva kuti hapana kuyambuka-reactivity. |
Zvishandiso Zvinoshanda: | SLAN-96P Chaiyo-Nguva PCR Systems(Hongshi Medical Technology Co., Ltd.) |