Mycobacterium Tuberculosis Rifampicin Resistance

Tsanangudzo Pfupi:

Kiti iyi inokodzera kuongororwa kwemhando yekuchinja kwehomozygous munharaunda ye507-533 amino acid codon yerpoB gene iyo inokonzeresa Mycobacterium tuberculosis rifampicin resistance.


Product Detail

Product Tags

Product name

HWTS-RT074A-Mycobacterium Tuberculosis Rifampicin Resistance Detection Kit (Fluorescence PCR)

Epidemiology

Rifampicin yakashandiswa zvakanyanya mukurapa varwere vepulmonary tuberculosis kubva mukupera kwema1970, uye ine simba rakakura.Yakave sarudzo yekutanga kupfupisa chemotherapy yevarwere vepulmonary tuberculosis.Kuramba kweRifampicin kunonyanya kukonzerwa nekushandurwa kwejene rerpoB.Kunyange zvazvo mishonga mitsva yekurwisa tibhii iri kuramba ichibuda, uye kushanda kwekiriniki kwevarwere vepulmonary tuberculosis kwakaramba kuchiwedzera, kuchine kushaikwa kwemishonga inorwisa tibhii, uye chiitiko chekushandisa zvinodhaka zvisina musoro mumakiriniki zvakanyanyisa.Zviri pachena kuti Mycobacterium tuberculosis muvarwere vane pulmonary tuberculosis haigoni kuurayiwa zvachose panguva yakakodzera, iyo inoguma inotungamirira kumadhigirii akasiyana-siyana ekudzivirira zvinodhaka mumuviri wemurwere, inowedzera nguva yechirwere, uye inowedzera ngozi yekufa kwemurwere.Kiti iyi yakakodzera kuongororwa kwechirwere cheMycobacterium tuberculosis pamwe nekuonekwa kwerifampicin resistance gene, zvinobatsira kunzwisisa kusamira zvakanaka kwemishonga yemycobacterium tuberculosis inobatwa nevarwere, uye nekupa dzimwe nzira dzekubatsira pakurapwa kwemishonga.

Epidemiology

 

Zita rechinangwa Reporter Quencher
Reaction BufferA Reaction BufferB Reaction BufferC
rpoB 507-514 rpoB 513-520 IS6110 FAM Hapana
rpoB 520-527 rpoB 527-533 / CY5 Hapana
/ / Kudzora mukati HEX(VIC) Hapana

 

Technical Parameters

Storage

≤-18℃ Murima

Sherufu-hupenyu

9 mwedzi

Type Type

Sputum

CV

<5%

LoD

rifampicin-resistant mhando yemusango: 2x103utachiona/mL

homozygous mutant: 2x103utachiona/mL

Zvakananga

Inoona mhuka yemusango mycobacterium tuberculosis uye nzvimbo dzekuchinja kwemamwe majini ekuramba zvinodhaka akadai se katG 315G>C\A, InhA-15C>T, mibairo yebvunzo inoratidza kusaramba rifampicin, zvinoreva kuti hapana kuyambuka-reactivity.

Zvishandiso Zvinoshanda:

SLAN-96P Chaiyo-Nguva PCR Systems(Hongshi Medical Technology Co., Ltd.)

Kuyerera Kwebasa


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