Kuchinja kwemajini eTEL-AML1 eHuman TEL-AML1
Zita rechigadzirwa
HWTS-TM016 Human TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Epidemiology
Acute lymphoblastic leukemia (ALL) ndiyo inonyanya kukonzera kenza muvana. Mumakore achangopfuura, acute leukemia (AL) yakachinja kubva kuMIC type (morphology, immunology, cytogenetics) kuenda kuMICM type (kuwedzera kwekuyedzwa kwemolecular biology). Muna 1994, zvakaonekwa kuti TEL fusion muvana yakakonzerwa ne nonrandom chromosome translocation t(12;21)(p13;q22) muB-lineage acute lymphoblastic leukemia (ALL). Kubva pakawanikwa AML1 fusion gene, TEL-AML1 fusion gene ndiyo nzira yakanakisisa yekutonga fungidziro yevana vane acute lymphoblastic leukemia.
Chiteshi
| FAM | Jini rekubatanidza reTEL-AML1 |
| ROX | Kudzora Kwemukati |
Magadzirirwo ehunyanzvi
| Kuchengetera | ≤-18℃ |
| Nguva yekuzorora | mwedzi mipfumbamwe |
| Rudzi rwemuenzaniso | muenzaniso wemwongo wemapfupa |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | Makopi 1000/mL |
| Kunyatsojeka | Hapana kusangana pakati pemakiti nemamwe majini ekubatanidza akaita seBCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, PML-RARa majini ekubatanidza. |
| Zvishandiso Zvinoshanda | Maitiro Ekushandisa Ezvinhu Zvehupenyu 7500 Masisitimu EPCR Enguva Yechokwadi Maitiro eApplied Biosystems 7500 PCR Systems Inokurumidza Munguva Yechokwadi Masisitimu ePCR eQuantStudio®5 Enguva Yechokwadi Masisitimu ePCR eSLAN-96P Enguva Yechokwadi Sisitimu yePCR yeLightCycler®480 Yenguva Yechokwadi Sisitimu yeKuona PCR yeLineGene 9600 Plus Yenguva Yechokwadi MA-6000 Chaiyo-Nguva Yekuyera Kupisa Kwemhepo Sisitimu yePCR yeBioRad CFX96 Yenguva Yechokwadi Sisitimu yePCR yeBioRad CFX Opus 96 Yenguva Yechokwadi |
Kufamba Kwebasa
Kiti yeRNAprep Pure Blood Total RNA Extraction Kit (DP433).
