Munhu PML-RARA Fusion Gene Mutation
Product name
HWTS-TM017AMunhu PML-RARA Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Epidemiology
Acute promyelocytic leukemia (APL) imhando yakakosha yeacute myeloid leukemia (AML). Inenge 95% yevarwere veAPL inoperekedzwa neshanduko yakakosha ye cytogenetic, iyo t (15; 17) (q22; q21), iyo inoita kuti PML gene pakromosome 15 uye retinoic acid receptor α gene (RARA) pachromosome 17 yakasanganiswa kuti iite PML-RARA fusion gene. Nekuda kwekutyora kwakasiyana kweiyo PML gene, iyo PML-RARA fusion gene inogona kukamurwa kuita refu mhando (L mhando), pfupi mhando (S mhando) uye akasiyana mhando (V mhando), inoverengera ingangoita 55%, 40% uye 5% zvichiteerana.
Channel
| FAM | PML-RARA fusion gene |
| ROX | Kudzora Kwemukati |
Technical Parameters
| Storage | ≤-18℃ Murima |
| Sherufu-hupenyu | 9 mwedzi |
| Type Type | mwongo |
| CV | <5.0 |
| LoD | 1000 Makopi/mL. |
| Zvakananga | Iko hakuna kuyambuka-reactivity nemamwe majini efusion BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, uye TEL-AML1 fusion genes. |
| Zvishandiso Zvishandiso | Applied Biosystems 7500 Chaiyo-Nguva PCR System Applied Biosystems 7500 Fast Real-Time PCR Systems Vadivelu Comedy QuantStudio®5 Chaiyo-Nguva PCR Systems SLAN-96P Chaiyo-Nguva PCR Systems (Hongshi Medical Technology Co., Ltd.) LightCycler®480 Chaiyo-Nguva PCR system LineGene 9600 Plus Chaiyo-Nguva PCR Detection System (FQD-96A, Hangzhou Bioer tekinoroji) MA-6000 Chaiyo-Nguva Quantitative Thermal Cycler (Suzhou Molarray Co., Ltd.) BioRad CFX96 Chaiyo-Nguva PCR System BioRad CFX Opus 96 Chaiyo-Nguva PCR System |
Kuyerera Kwebasa
Inokurudzirwa kuburitsa reagent: RNAprep Rakachena Ropa Rakazara RNA Extraction Kit (DP433). Kubvisa kunofanirwa kuitwa maererano neIFU.
