Carbapenase

Tsananguro pfupi:

Kit iyi inoshandiswa pakuona mhando ye NDM, KPC, OXA-48, IMP uye VIM carbapenemases inogadzirwa mumasampuli emabhakitiriya akawanikwa mushure mekurimwa mu vitro.

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HWTS-OT085E/F/G/H -Kit yekuona Carbapenemase (Colloidal Gold)

Epidemiology

Mishonga inorwisa mabhakitiriya yeCarbapenem imishonga isingawanzoitiki yeβ-lactam ine hutachiona hwakakura uye ine simba guru rekurwisa mabhakitiriya.^[1]Nekuda kwekugadzikana kwayo ku β-lactamase uye chepfu shoma, yave imwe yemishonga inonyanya kukosha yekurapa hutachiona hwakasimba hwebhakitiriya. Carbapenems yakasimba zvikuru ku plasmid-mediated extended-spectrum β-lactamases (ESBLs), ma chromosomes uye plasmid-mediated cephalosporinases (AmpC enzymes)^[2].

Magadzirirwo ehunyanzvi

Nzvimbo yakanangwa	NDM, KPC, OXA-48, IMP uye VIM carbapenemases
Tembiricha yekuchengetedza	4℃ -30℃
Rudzi rwemuenzaniso	Mienzaniso yebhakitiriya yakawanikwa mushure mekurimwa
Nguva yesherufu	mwedzi makumi maviri nemana
Zviridzwa zvekubatsira	Hazvidikanwi
Zvimwe Zvinoshandiswa	Hazvidikanwi
Nguva yekuona	Mienzaniso yebhakitiriya yakawanikwa mushure mekurimwa
LoD	Rudzi rweNDM:0.15ng/mL Rudzi rweKPC: 0.4ng/mL Rudzi rweOXA-48:0.1ng/mL Rudzi rweIMP:0.2ng/mL Rudzi rweVIM:0.3ng/mL.
Mhedzisiro yehoko	Kune NDM, KPC, OXA-48 mhando ye carbapenemase, hapana hook effect inowanikwa iri pakati pe100ng/mL; kune IMP, VIM mhando ye carbapenemase, hapana hook effect inowanikwa iri pakati pe1μg/mL.