PCT/IL-6 Yakasanganiswa

PCT ndiyo inotangira calcitonin, inova glycoprotein inoumbwa ne116 amino acids.Huwandu hwemamorekuru hunosvika 12.8kd.Haina basa rehomoni.Pasi pemamiriro ehupenyu, PCT inonyanya kugadzirwa uye inovanzwa nemasero eC thyroid.Munguva yehutachiona hwehutachiona, macrophages uye monocytes muchiropa, lymphocytes uye endocrine masero mumapapu uye mumatumbo emukati anogadzira uye anobudisa yakawanda yePCT pasi pechiito che endotoxin, tumor necrosis factor-α uye interleukin-6, zvichiita kuti kuwedzerwa kukuru. mune serum PCT mazinga.
Interleukin-6 inonzi cytokine inoratidzwa neinnate immune system panguva yekukuvara kwekutanga uye hutachiona.Inobudiswa ne fibroblasts, monocytes/macrophages, T lymphocytes, B lymphocytes, epithelial masero, keratinocytes, uye masero akasiyana-siyana emamota.IL-6 inoumbwa nemaketani maviri eglycoprotein, imwe iketani α ine molecular uremu hwe80kd;imwe yacho iketani yeβ ine huremu hwema molecular 130kd[5].Kana muviri wemunhu uchimutswa nekuzvimba, IL-6 mazinga anosimuka nekukurumidza, izvo zvinopindirana neacute chikamu chemhinduro yechiropa uye inosimudzira kugadzirwa kweacute phase mapuroteni akadai seC-reactive protein (CRP) uye serum amyloid A (SAA). )Naizvozvo, IL-6 ndiyo yekutanga chiratidzo kusimuka kana kuzvimba kuchiitika.