Chii chinonzi denguekupindwa nechandouye DENVvirus?
Dengue fivha inokonzerwa nehutachiona hwedengue (DENV), hunonyanya kutapuriranwa kuvanhu kuburikidza nekurumwa neumhutu hwechikadzi hune utachiona, kunyanya Aedes aegypti neAedes albopictus.
Kune marudzi mana akasiyana ehutachiona (DENV-1, DENV-2, DENV-3, uye DENV-4). Kutapukirwa nehutachiona hweserotype imwe chete kunoita kuti munhu asakwanise kurwisa utachiona hweserotype iyoyo asi kwete mamwe.
Dengue inonyanya kupararira kuburikidza nekurumwa neumhutu. Zvinhu zvikuru zvinokanganisa kutapurirana kwayo zvinosanganisira:
Vekitori:IyoAedes aegyptiUmhutu hunokura zvakanaka mumaguta uye hunobereka mumvura isina mvura.Aedes albopictusinogonawo kutapurirana hutachiona asi haiwanzoitiki.
Kutapurirana kweUmhutu Kubva kuMunhu:Kana umhutu hukaruma munhu ane hutachiona, hutachiona hunopinda muumhutu uye hunogona kutapuriranwa kune mumwe munhu mushure menguva yekuzvara kwechirwere ichi kwemazuva angangoita masere kusvika gumi nemaviri.
Sei tichirwara nedengue fever kunyangwe munyika dzisiri dzemuno?
Kuchinja kweMamiriro ekunze: Kukwira kwekushisa kwepasi rose kuri kuwedzera nzvimbo dzekugara kwemhuka idziUmhutu hweAedes,mishonga mikuru yedengue.
Kufamba Nekutengeserana Pasi Pose: Kuwedzera kwekufamba nekutengeserana kwenyika dzakasiyana-siyana kunogona kukonzera kuunzwa kweumhutu hunotakura dengue kana vanhu vane hutachiona munzvimbo dzisiri dzemunzvimbo dzinopisa.
Kukura kwemaguta: Kukurumidza kukura kwemaguta pasina mvura yakakwana, zvichiita kuti umhutu hubereke.
Kujairana neUmhutu: Umhutu hweAedes, kunyanyaAedes aegyptiuyeAedesalbopictus, vari kuchinja mamiriro ekunze ane mwero munzvimbo dzakadai sedzimwe nzvimbo dzeEurope neNorth America.
Zvinhu izvi zvinobatsira pamwe chete mukuwedzera kwekuvapo kwedengue munzvimbo dzisiri dzemunzvimbo dzinopisa.
Nzira yekuziva nekurapa dengue fever?
Kuongororwa kwechirwere chedengue kunogona kuoma nekuda kwezviratidzo zvayo zvisiri zvega, izvo zvinogona kutevedzera zvimwe zvirwere zvinotapukira.
Zviratidzo:Zviratidzo zvekutanga zvinowanzoonekwa mazuva mana kusvika gumi mushure mekutapukirwa zvinosanganisira fivha yakanyanya, musoro wakakomba, kurwadziwa kwemashure nedumbu, kurwadziwa kwemajoini netsandanyama, mapundu, uye kubuda ropa zvishoma. Muzviitiko zvakakomba, dengue inogona kufambira mberi kuita dengue hemorrhagic fever (DHF) kana dengue shock syndrome (DSS), iyo inogona kuisa hupenyu panjodzi. Kuzivikanwa nekukurumidza kunobatsira mukugadzirisa zviratidzo zvisati zvanyanya kuipa.
Kuonekwamtsika dzedengue:
SMiedzo ye erology:Kuona masoja ekudzivirira chirwere (IgM neIgG) kubva kuDENV, IgM ichiratidza hutachiona huchangobva kuitika uye IgG ichiratidza kuti munhu agara akasangana nechirwere ichi. Miedzo iyi inowanzo shandiswa mukudzivirira chirwere ichi.makirinikiuyemarabhoritari ari pakatikusimbisa hutachiona huripo kana hwakamboitika panguva yekupora kana kune vanhu vasina zviratidzo vane nhoroondo yekubatwa nechirwere ichi.
Miedzo yeAntigen yeNS1:Kuona puroteni isina chimiro 1 (NS1) pakutanga kwehutachiona, inoshanda senzira yekuongorora chirwere nekukurumidza, yakakodzera kuonekwa nekukurumidza mukati memazuva 1-5 ekutanga echiratidzo. Miedzo iyi inowanzoitwa munzvimbo dzekutarisirazvakaita semakiriniki, zvipatarauyemadhipatimendi ekukurumidzirakuti munhu aite sarudzo nekukurumidza uye atange kurapwa.
Miedzo yeNS1 + IgG/IgM:Kuona hutachiona huripo uye hwakambovapo nekuyedza mapuroteni ehutachiona uye masoja ekudzivirira chirwere ari muropa, zvichiita kuti zvibatsire pakusiyanisa hutachiona hwazvino uye hwakamboonekwa, kana kuona hutachiona hwechipiri. Izvi zvinowanzoshandiswa muzvipatara, makirinikiuyemarabhoritari ari pakatikuti pave nekuongororwa kwakazara kwechirwere.
Miedzo yeMolekyulu:Kuona RNA yehutachiona muropa, inoshanda zvakanyanya mukati mevhiki yekutanga yekurwara, uye inoshandiswa pakutanga kwehutachiona kuti isimbiswe zvakajeka, kunyanya muzviitiko zvakakomba. Miedzo iyi inonyanya kuitwa mumarabhoritari ari pakatinehunyanzvi hwekuongorora mamorekuru nekuda kwekudiwa kwemichina yakakosha.
Kutevedzana kwezviitiko:Inoziva majini eDENV kuti idzidze hunhu hwayo, kusiyana kwayo, uye kushanduka-shanduka kwayo, zvakakosha pakutsvagisa kwezvirwere, kuferefeta kubuda kwechirwere, uye kutevedzera shanduko dzehutachiona uye maitiro ekupararira kwehutachiona. Bvunzo iyi inoitwa mumarabhoritari ekutsvagisauyemarabhoritari ehutano hweveruzhinji akasarudzikakuti zviongororwe zvakadzama nezve genomic uye zvinangwa zvekutarisa.
Parizvino, hapana mushonga chaiwo wekudzivirira dengue. Varapi vanotarisa pakubatsira vanhu vane chirwere ichi, kuderedza marwadzo uye kutarisana nemurwere. Zvinofanira kucherechedzwa kuti kuziva hutachiona hwedengue nekukurumidza kunogona kudzivirira matambudziko makuru.
Macro & Micro-Test iri kupa mishonga yakasiyana-siyana yeRDTs, RT-PCR uye Sequencing yekuongorora dengue uye kutarisa denda:
Hutachiona hweDengue I/II/III/IVKiti Yekuona Asidhi- mvura/yakasanganiswa;
Dengue NS1 Antigen, IgM/IgG AntibodyKiti yekuona zvinhu zviviri;
HWTS-FE029-Kiti yekuona maantigen eDengue NS1
Mhando dzeMavhairasi eDengue 1/2/3/4 Whole Genome Enrichment Kit (Multiplex Amplification Method)
Pepa rinoenderana naro:
https://www.sciencedirect.com/science/article/abs/pii/S0168170218300091?via%3Dihub
Nguva yekutumira: Gumiguru-21-2024