Chidzidzo chakakosha chakabudiswa munguva pfupi yapfuura muLancetyakaratidza chokwadi chinobaya mwoyo:Vanhu vanosvika mamiriyoni 1.27 vakafa muna 2019zvaikonzerwa zvakananga nekuramba utachiona (AMR)Zvinotonyanya kutyisa,73% yerufu urwu rwakakonzerwa nezvirwere zvitanhatu chete:

1.Escherichia coli

2.Staphylococcus aureus

3.Klebsiella pneumoniae

4.Streptococcus pneumoniae

5.Acinetobacter baumannii

6.Pseudomonas aeruginosa

Pakati pavo,Klebsiella pneumoniae (KPN), Acinetobacter baumannii (Aba)uyePseudomonas aeruginosa (PA)Zvirwere izvi zviri kuramba zvichipararira zvakanyanya muzvirwere zvinotapukira muzvipatara uye kusakwanisa kushandisa mishonga yakawanda.carbapenems—mudziviriro wedu wekupedzisira—uri kutyisidzira hutano hwepasi rose zvakanyanya.

Kunzwisisa KPN, Aba, uye PA

-Klebsiella pneumoniae (KPN)

KPN chirwere chinowanzo shandiswa pakurwisa matambudziko emuviri uye ndicho chinokonzera matambudziko aya.chipatara chakatorwahutachionaKana dziviriro yemuviri wemunhu ikakanganiswa, inogona kupinda nemunzira yekufema, zvichikonzera pneumonia, hutachiona hweropa, uye sepsis. Chinonyanya kushungurudza inyaya iyi.mhando yehutachiona hwakanyanya hweHvKp ST23, iyo inowanzo takura majini e-carbapenase akadai seKPC, NDM, OXA-48, uye IMP, zvichiita kuti kurapwa kuve kwakaoma zvikuru.

-Acinetobacter baumannii (Aba)

Aba chirwere chinopararira zvakanyanya muchipatara chinogona kurarama pamusoro kwenguva yakareba. Ndicho chikonzero chikuru chechirwere ichi.pneumonia inokonzerwa neventilator (VAP)uye hutachiona hune chekuita neICU. Kugona kwayo kukuru kuwana majini ekudzivirira chirwere kwakaita kuti ive imwe yedzine njodzi huruzvipembenene zvisingapindi mishonga yakawanda (MDR), ine simba rekudzivirira carbapenem rinodarika50% mune dzimwe nzvimbo.

-Pseudomonas aeruginosa (PA)

PA ibhakitiriya risingavirisi Gram-negative rinokonzerahutachiona hwepazasi hwekufema, kunyanya muvarwere vane dziviriro yemuviri yakakanganisika. Kuchinjika kwayo, kukurumidza kuchinja, uyekugona kugadzira biofilmzvinoita kuti hutachiona huome kubvisa.Carbapenem-resistant PA (CRPA)ichiri dambudziko rekiriniki rinogara riripo pasi rose.

Kupararira Kwakaita Utachiona Uhu

Utachiona hweMDR hunopararira kuburikidza ne:

-Nzvimbo dzechipatara:midziyo yakasviba, nzvimbo, uye maoko evashandi vehutano

-Kubata zvakananga:varwere vane hutachiona kana kuti vane zviratidzo zvechirwere

-Madonhwe ekufema:kunyanya kune marudzi ane chekuita nemabayo

-Maitiro ekupinda muchivande:mafekitori, macatheter, uye zvishandiso zvekuvhiya

Matambudziko muKurapwa

-Kuramba kweCarbapenem

Carbapenems inoonekwa semishonga inorwisa mabhakitiriya yekurapa kwekupedzisiraKubuda kwebhakitiriya rinogadzira carbapenemase kwakaderedza kushanda kwaro zvakanyanya.

-Sarudzo Dzekurapa Dzishoma

-Polymyxins (semuenzaniso, colistin): inoshanda asi ine chepfu yakawanda

-Tigecycline: zviratidzo zvishoma

-Mishonga mitsva (cefiderokol, sulbactam-durlobactam): inovimbisa asi kuwanikwa kwayo kushoma.

Kudzivirira uye kuona chirwere ichi nekukurumidza kwave kwakakosha kupfuura kare.

Kudiwa Kwekuwanikwa Nokukurumidza Uye Kwakarurama

Utachiona uhu hunokonzera kufa kwakawanda kunokonzerwa neAMR pasi rose, zvichiratidza kuti kudiwa kukuru kwekuongororwa nekukurumidza uye kwakavimbikakutungamira kurapwa kwakakodzera.

Kuwanikwa Kwechirwere Chekare Kunoponesa Upenyu

Kuti tigadzirise izvi zvinodiwa pakurapa nekukurumidza,Macro & Micro-Test's KPN, Aba, PA & Drug Resistance Genes Multiplex Detection Kitinopa mhinduro ine simba.

Mhinduro itsva,Kiti yeKuona Multiplex yeMacro & Micro-Test, zvinoita kuti zvikwanise kuzivikanwa panguva imwe chete kweKPN, Aba, PA, uye majini akakosha ecarbapenemase-KPC, NDM, OXA-48uyeIMP.

Zvakanakira Zvikuru:

• Kuonekwa zvakananga kubva kumasampuli emapute, kubvisa maitiro ekurera kwenguva refu.
• Kunyanya kutsanangurwa uye kunzwa(LoD: 1000 CFU/mL) kuti uwane mhinduro dzakarurama.
• Nguva yekukurumidza kupindura—zvinoguma ne35 chete-50maminitsi.
• Inoenderana nemasisitimu makuru ePCR, zvichiita kuti zvive nyore kuwana.

Kudanwa Kwechiito: Kusimbisa Kurwisa Superbugs

YepamusoroKiti yeKuona MultiplexsnaMacro & Micro-Test inopa mukana wakakosha mukuona hutachiona husingaurayiwi nemishonga nekukurumidza uye nemazvo, inogonesa kuongororwa nekukurumidza, kuongororwa nekukurumidza, uye nzira dzekurapa dzakanangana, izvo zvinozopedzisira zvavandudza mhedzisiro yemurwere uye kudzora kupararira kwekusaravira kwemishonga inorwisa mabhakitiriya.

Batanai muhondo yekurwisa kusakwanisa kurwisa mabhakitiriya—shongedzai rabhoritari yenyu nechishandiso chemazuva ano chekuongorora.

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