Kusakwanisa kurwisa mabhakitiriya (AMR) kwave chimwe chezvinhu zvinotyisa zvikuru pahutano hwevanhu muzana rino remakore, zvichikonzera kufa kwevanhu vanodarika mamiriyoni 1.27 gore rega rega uye zvichikonzera kufa kwevanhu vanosvika mamiriyoni mashanu—dambudziko guru iri rehutano repasi rose rinoda kuti tiite chimwe chinhu nekukurumidza.
Vhiki reKuzivisa Nezve AMR Pasi Rose (Mbudzi 18-24), vatungamiriri vezvehutano pasi rose vanobatana mukukurudzira kwavo:"Chitoita Izvozvi: Chengetedza Zvatiripo Iye Zvino, Chengetedza Remangwana Redu."Dingindira iri rinosimbisa kukosha kwekukurumidzira kugadzirisa AMR, zvichireva kushanda pamwe chete muzvikamu zvehutano hwevanhu, hutano hwemhuka, uye zvakatipoteredza.
Njodzi yeAMR inodarika miganhu yenyika nenzvimbo dzehutano. Sekureva kweongororo yazvino yeLancet, pasina nzira dzinoshanda dzekurwisa AMR,Kufa kwevanhu vakawanda pasi rose kunogona kusvika mamiriyoni makumi matatu nemapfumbamwe panosvika gore ra2050, nepo mutengo wepagore wekurapa hutachiona husingarapike mishonga uchitarisirwa kukwira kubva pamadhora mabhiriyoni makumi matanhatu nematanhatu ($66 bhiriyoni) kusvika pamadhora makumi maviri nematanhatu ($66 bhiriyoni)mabhiriyoni zana nemakumi mashanu nemapfumbamwe emadhora.
Dambudziko reAMR: Chokwadi Chikuru Chiri Kuseri Kwenhamba
Kusakwanisa kurwisa utachiona (AMR) kunoitika kana tupukanana—mabhakitiriya, mavhairasi, tupukanana, uye howa—tisingachapinduri nemishonga yemazuva ano inorwisa utachiona. Dambudziko iri rehutano pasi rose rasvika padanho rinotyisa:
-Maminetsi mashanu ega ega, Munhu mumwe chete anofa nehutachiona husingarapike nemishonga inorwisa mabhakitiriya
-Na2050, AMR inogona kuderedza GDP yepasi rose ne3.8%
-96% yenyika(186 vese) vakapinda muongororo yepasi rose yekutevera AMR ya2024, zvichiratidza kuzivikanwa kwakapararira kwenjodzi iyi.
-Mumakamuri evarwere vane chirwere chepfungwa mune dzimwe nzvimbo,anopfuura 50% emabhakitiriya anopararirakuratidza kusakwanisa kurwisa mushonga unorwisa mabhakitiriya mumwe chete
Kukundikana Kwemishonga Inorwisa Mabhakitiriya: Nzira Dzekudzivirira Dziviriro Yezvipembenene
Mishonga inorwisa mabhakitiriya inoshanda nekutarisa maitiro akakosha emabhakitiriya:
-Kugadzirwa kweMadziro Esero: Mapenicillin anokuvadza madziro emasero ebhakitiriya, zvichikonzera kuputika kwebhakitiriya nerufu
-Kugadzirwa kweMapuroteni: Tetracyclines nema macrolides zvinodzivisa mabhakitiriya e ribosomes, zvichimisa kugadzirwa kweprotein
-Kudzokorora kweDNA/RNA: Fluoroquinolones inodzivirira ma enzyme anodiwa pakuumbwa kweDNA rebhakitiriya
-Kuvimbika kweMembrane yeSero: Polymyxins inokuvadza membrane yemasero ebhakitiriya, zvichikonzera kufa kwemasero
-Nzira dzeMetabolic: Sulfonamides inovhara maitiro ebhakitiriya akakosha senge folic acid synthesis
Zvisinei, kuburikidza nekusarudza kwechisikigo uye kushanduka kwemajini, mabhakitiriya anogadzira nzira dzakawanda dzekudzivirira mabhakitiriya, kusanganisira kugadzira ma enzymes anodzima, kushandura zvinangwa zvemishonga, kuderedza kuunganidzwa kwemishonga, uye kugadzira biofilms.
Carbapenemase: "Chombo Chikuru" muDambudziko reAMR
Pakati penzira dzakasiyana-siyana dzekudzivirira, kugadzirwa kwecarbapenemasesZvinonyanya kunetsa. Ma enzyme aya anonyungudutsa mishonga inorwisa mabhakitiriya inonzi carbapenem—inowanzoonekwa semishonga "yekupedzisira". MaCarbapenema anoshanda se "zvombo zvepamusoro" zvebhakitiriya, achipwanya mishonga inorwisa mabhakitiriya asati apinda mumasero ebhakitiriya. Mabhakitiriya ane ma enzyme aya—akadai seKlebsiella pneumoniaeuyeAcinetobacter baumannii—inogona kurarama uye kuberekana kunyangwe kana ikabatwa nemishonga inorwisa mabhakitiriya ine simba zvikuru.
Zvinotonyanya kushamisa ndekuti, majini anogadzira carbapenemases ari pamajini anofambiswa anogona kutamira pakati pemarudzi akasiyana ebhakitiriya,kukurumidzisa kupararira kwehutachiona husingaurayiwi nemishonga yakawanda pasi rose.
Kuongorora chirweres: Mutsetse Wekutanga Wekudzivirira Mukutonga kweAMR
Kuongorora chirwere nemazvo uye nekukurumidza kwakakosha pakurwisa AMR. Kuziva mabhakitiriya anodzivirira chirwere panguva yakakodzera kunogona:
-Kurapwa kwakarurama, kudzivirira kushandiswa kwemishonga inorwisa mabhakitiriya zvisina kunaka
-Isa matanho ekudzivirira hutachiona kudzivirira kutapurirana kwehutachiona husingaurayiwi
-Ongorora maitiro ekuramba kuti ubatsire sarudzo dzehutano hweveruzhinji
Mhinduro Dzedu: Zvishandiso Zvitsva zveKurwisa AMR Zvakanyatsonaka
Kuti vagadzirise dambudziko riri kukura reAMR, Macro & Micro-Test yakagadzira makit matatu matsva ekuona carbapenemase anosangana nezvinodiwa zvakasiyana zvekiriniki, zvichibatsira varapi vehutano kuona mabhakitiriya anodzivirira chirwere nekukurumidza uye nemazvo kuti vave nechokwadi chekupindira panguva yakakodzera uye kuvandudza mhedzisiro yemurwere.
1. Kiti Yekuona Carbapenemase (Colloidal Gold)
Inoshandisa tekinoroji yecolloidal gold kuti ionekwe nekukurumidza uye nenzira yakavimbika yecarbapenemase. Yakakodzera kuzvipatara, makiriniki, uye kunyangwe kushandiswa kumba, zvichiita kuti kuongororwa kuve nyore uye kwakarurama.
Zvakanakira Zvikuru:
-Kuonekwa Kwakazara: Panguva imwe chete inoona majini mashanu ekudzivirira chirwere—NDM, KPC, OXA-48, IMP, uye VIM.
-Mhedzisiro Inokurumidza: Inopa mhinduro mukatiMaminetsi gumi nemashanu, inokurumidza zvikuru kupfuura nzira dzechinyakare (zuva 1-2)
-Kushanda Kuri Nyore: Hapana michina yakaoma kana kudzidziswa kwakakosha kunodiwa, yakakodzera nzvimbo dzakasiyana-siyana
-Kururama Kwakanyanya: 95% kunzwisiswa kwechirwere pasina zviratidzo zvenhema kubva kumabhakitiriya akajairika seKlebsiella pneumoniae kana Pseudomonas aeruginosa
2. Kiti Yekuona Majini Anodzivirira Carbapenem (Fluorescence PCR)
Yakagadzirirwa kuongorora majini akadzama ekusagona kurwisa carbapenem. Yakanakira kuongororwa kwakazara mumakiriniki, ichipa ruzivo rwakarurama rwemajini akawanda anodzivirira carbapenem.
Zvakanakira Zvikuru:
-Kuenzanisa Kunochinjika: Kuonekwa zvakananga kubvamakoroni akachena, sputum, kana rectal swabs—hapana kurimwazvinodiwa
-Kuderedza Mutengo: Inoona majini matanhatu akakosha ekudzivirira chirwere (NDM, KPC, OXA-48, OXA-23) IMP, uye VIM mubvunzo mumwe chete, ichibvisa bvunzo dzisina kudzokororwa.
-Kunzwisisa Kwakanyanya uye KunyatsojekaMuganho wekuona wakaderera se1000 CFU/mL, hapana kusangana kwemasero nemamwe majini ekudzivirira akadai seCTX, mecA, SME, SHV, uye TEM.
-Kuenderana Kwakakura: Inoenderana neMuenzaniso weMhinduroAIO 800 inozvigadzira yoga zvizere POCT yemamorekuru uye zvishandiso zvikuru zvePCR
3. Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa uye Resistance Genes Multiplex Detection Kit (Fluorescence PCR)
Kit iyi inobatanidza kuzivikanwa kwebhakitiriya uye nzira dzekudzivirira chirwere dzinoenderana nadzo mukuita kumwe chete kwakapfava kwekuongorora chirwere zvinobudirira.
Zvakanakira Zvikuru:
-Kuonekwa Kwakazara: Panguva imwe chete inoonahutachiona hutatu hunokosha hwebhakitiriya—Klebsiella pneumoniae, Acinetobacter baumannii, uye Pseudomonas aeruginosa—uye inoona majini mana akakosha ecarbapenemase (KPC, NDM, OXA48, uye IMP) muongororo imwe chete.
-Kunzwa Kwakanyanya: Inokwanisa kuona DNA yebhakitiriya pahuwandu hwakaderera kusvika ku1000 CFU/mL
-Inotsigira Sarudzo yeKliniki: Inobatsira kusarudza mishonga inoshanda inorwisa utachiona kuburikidza nekuziva nekukurumidza mhando dzehutachiona husingaurayiwi nemishonga
-Kuenderana Kwakakura: Inoenderana neMuenzaniso weMhinduroAIO 800 inozvigadzira yoga zvizere POCT yemamorekuru uye zvishandiso zvikuru zvePCR
Makiyi aya ekuona chirwere anopa nyanzvi dzehutano zvishandiso zvekugadzirisa AMR pamatanho akasiyana-siyana—kubva pakuongororwa nekukurumidza kusvika pakuongororwa kwemajini—zvichivimbisa kupindira panguva yakakodzera uye kuderedza kupararira kwebhakitiriya rinodzivirira chirwere.
Kurwisa AMR nePrecision Diagnostics
KuMacro & Micro-Test, tinopa makit ekuongorora epamusoro-soro anopa vanopa hutano ruzivo rwekukurumidza uye rwakavimbika, zvichigonesa kugadzirisa kurapwa nenguva uye kudzora hutachiona zvinobudirira.
Sezvakasimbiswa panguva yeWorld AMR Awareness Week, zvatinosarudza nhasi ndizvo zvicharatidza kugona kwedu kuchengetedza zvizvarwa zviripo uye zveramangwana kubva munjodzi yekusagona kurwisa mabhakitiriya.
Batanai mukurwisa kusakwanisa kurwisa utachiona—hupenyu hwese hunoponeswa hunokosha.
For more information, please contact: marketing@mmtest.com
Nguva yekutumira: Mbudzi-19-2025