Antimicrobial resistance (AMR) yave imwe yekutyisidzira kukuru kwehutano hweveruzhinji muzana rino ramakore, zvichikonzera kufa kwevanhu vanopfuura mamirioni 1.27 gore rega rega uye zvichikonzera kufa kunoda kusvika mamirioni mashanu - dambudziko rehutano repasi rose rinoda kuti tiite nekukurumidza.
Iyi World AMR Vhiki Yekuzivisa (Mbudzi 18-24), vatungamiriri vehutano pasi rose vanobatana mukufona kwavo:"Ita Izvozvi: Dzivirira Iripo Yedu, Chengetedza Ramangwana Redu."Dingindira iri rinosimbisa kukurumidza kugadzirisa AMR, ichida kuedza kwakarongeka muhutano hwevanhu, hutano hwemhuka, uye zvikamu zvezvakatipoteredza.
Kutyisidzira kwe AMR kunodarika miganhu yenyika uye nzvimbo dzehutano hwehutano. Zvinoenderana neazvino Lancet kudzidza, pasina kupindira kunoshanda kurwisa AMR,Kuwedzera kwekufa kwepasi rose kunogona kusvika 39 miriyoni ne2050, nepo mutengo wepagore wekurapa zvirwere zvisingaurayiwi nemishonga unofungidzirwa kuti uchakwira kubva pamabhiriyoni makumi matanhatu nematanhatu emadhora$159 bhiriyoni.
Dambudziko reAMR: Chokwadi Chakanyanya Kuseri KweNhamba
Antimicrobial resistance (AMR) inoitika apo tupukanana—mabhakitiriya, mavhairasi, utachiona, uye fungi—zvisingachapinduri kumishonga yakajairika inorwisa utachiona. Iyi dambudziko rehutano pasi rose rasvika pamwero unotyisa:
-Ese maminetsi mashanu, munhu mumwe anofa nechirwere chisingaurayiwi nemishonga inorwisa mabhakitiriya
-By2050AMR inogona kuderedza GDP yepasi rose ne3.8%
-96% yenyika(186 yakazara) vakapinda mu2024 pasi rose AMR tracking ongororo, zvichiratidza kucherechedzwa kwakapararira kwekutyisidzira uku.
-Munzvimbo dzinochengeterwa varwere zvakanyanya mune mamwe matunhu,pamusoro pe50% yemabhakitiriya isolatesratidza kusabvuma mushonga mumwe chete
Maitirwo EmaAntibiotics Anokundikana: Microorganisms 'Defence Mechanisms
Mishonga inorwisa mabhakitiriya inoshanda nekutarisa maitiro akakosha ehutachiona:
-Sero Wall Synthesis: Penicillin inovhiringidza madziro emasero ebhakitiriya, zvichiita kuti utachiona hutsemuka uye rufu
-Kugadzirwa kweproteinTetracyclines uye macrolides anovharira mabhakitiriya ribosomes, kumisa mapuroteni synthesis
-DNA/RNA Replication: Fluoroquinolones inhibit enzymes inodiwa kuti bhakitiriya DNA replication
-Sero Membrane Kutendeseka: Polymyxins inokuvadza bacterial cell membranes, zvichiita kuti sero kufa
-Metabolic nzira: Sulfonamides inovharira maitiro akakosha ebhakitiriya se folic acid synthesis
Zvisinei, kuburikidza nekusarudzwa kwechisikigo uye kushanduka kwemajini, mabhakitiriya anogadzira nzira dzakawanda dzekudzivisa mishonga inorwisa mabhakitiriya, kusanganisira kubudisa ma enzymes asingashande, kushandura zvinodhaka, kuderedza kuunganidza zvinodhaka, nekugadzira biofilms.
Carbapenemase: Iyo "Super Weapon" muAMR Dambudziko
Pakati pemaitiro akasiyana-siyana ekupikisa, kugadzirwa kwecarbapenemasinonyanya kunetsa. Aya ma enzymes hydrolyze carbapenem antibiotics-inowanzoonekwa se "yekupedzisira-mutsara" mishonga. Carbapenemases inoshanda sebhakitiriya "zvombo zvepamusoro," kuputsa mishonga inorwisa mabhakitiriya isati yapinda mumasero ebhakitiriya. Utachiona hunotakura maenzayimu aya—saKlebsiella pneumoniaeuyeAcinetobacter baumannii-inogona kurarama uye kuwanda kunyange kana yaiswa kune mishonga inorwisa mabhakitiriya ine simba.
Zvinotonyanya kutyisa, majini encoding carbapenemases ari pane mobile genetic zvinhu zvinogona kufambisa pakati pemhando dzakasiyana dzebhakitiriya,kukurumidza kupararira kwepasi rose kwehutachiona husingaurayiwi nemishonga yakawanda.
Diagnostics: Mutsara wekutanga weDziviriro mu AMR Control
Kwakarurama, kukurumidza kuongororwa kwakakosha mukurwisa AMR. Kuzivikanwa panguva yakakodzera kwehutachiona hwehutachiona hunogona:
-Nhungamiro chaiyo yekurapa, kudzivirira kusashanda kwemishonga inorwisa mabhakitiriya
-Kushandisa matanho ekudzivirira hutachiona kudzivirira kutapurirana kwebhakitiriya rinopesana
-Monitor kuramba maitiro kuzivisa hutano hweveruzhinji sarudzo
Yedu Mhinduro: Zvishandiso Zvitsva zve Precision AMR Combat
Kugadzirisa dambudziko riri kukura re AMR, Macro & Micro-Test yakagadzira matatu matsva ekuona carbapenemase kits inosangana nezvinodiwa zvekiriniki zvakasiyana, kubatsira vatapi vehutano nekukurumidza uye nenzira kwayo kuona mabhakitiriya anopokana kuti ave nechokwadi chekupindira panguva uye kuvandudza mhedzisiro yevarwere.
1. Carbapenemase Detection Kit (Colloidal Gold)
Inoshandisa colloidal goridhe tekinoroji yekukurumidza, yakavimbika carbapenemase kuona. Inokodzera zvipatara, makiriniki, uye kunyange kushandiswa kwemba, kurerutsa nzira yekuongorora nehupamhi hwepamusoro.
Core Advantages:
-Comprehensive Detection: Panguva imwe chete inozivisa shanu dzekuramba majini — NDM, KPC, OXA-48, IMP, uye VIM
-Rapid Results: Inopa mhinduro mukatiMaminitsi gumi nemashanu, zvakakurumidza kupfuura nzira dzechinyakare (1-2 mazuva)
-Easy Operation: Hapana midziyo yakaoma kana kudzidziswa kwakasarudzika kunodiwa, yakakodzera kune akasiyana marongero
-Kururama Kwepamusoro: 95% senitivity pasina manyepo enhema kubva kune akajairika mabhakitiriya seKlebsiella pneumoniae kana Pseudomonas aeruginosa
2. Carbapenem Resistance Gene Detection Kit (Fluorescence PCR)
Yakagadzirirwa in-deep genetic analysis of carbapenem resistance. Yakanakira kuongororwa kwakadzama mumakiriniki marabhoritari, ichipa kunyatsoonekwa kweakawanda carbapenem kuramba majini.
Core Advantages:
-Flexible Sampling: Kuonekwa kwakananga kubvadzakachena makoloni, sputum, kana rectal swabs-pasina tsikazvinodiwa
-Kuderedza Mutengo: Inoona matanhatu akakosha ekupikisa majini (NDM, KPC, OXA-48, OXA-23) IMP, uye VIM muyedzo imwe chete, kubvisa kuyedza kusingadzoreki.
-High Sensitivity uye Kunyatsojeka: Yekuona muganho wakaderera se1000 CFU/mL, hapana kuyambuka-reactivity nemamwe marudzi ekuramba seCTX, mecA, SME, SHV, uye TEM.
-Broad Compatibility: Inopindirana neSample-ye-MhinduroAIO 800 yakazara otomatiki mamorekuru POCT uye makuru PCR zviridzwa
3. Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa uye Resistance Genes Multiplex Detection Kit (Fluorescence PCR)
Iyi kit inosanganisa kuziviswa kwebhakitiriya uye nzira dzekupikisa dzakabatanidzwa kuita imwe nzira yakagadziridzwa yekuongororwa kwakanaka.
Core Advantages:
-Comprehensive Detection: Panguva imwe chete inozivisamatatu akakosha mabhakitiriya pathogens— Klebsiella pneumoniae, Acinetobacter baumannii, uye Pseudomonas aeruginosa — uye inoona mana akakosha ecarbapenemase genes (KPC, NDM, OXA48, uye IMP) mune imwe bvunzo.
-High Sensitivity: Inokwanisa kuona bhakitiriya DNA munzvimbo dzakaderera se1000 CFU/mL
-Inotsigira Clinical Sarudzo: Inobatsira kusarudzwa kwemishonga inorwisa utachiona hunobudirira kuburikidza nekuzivikanwa kwekutanga kwemhando dzisingaperi
-Broad Compatibility: Inopindirana neSample-ye-MhinduroAIO 800 yakazara otomatiki mamorekuru POCT uye makuru PCR zviridzwa
Aya makiti ekuona anopa vashandi vehutano zvigadziriso zvekugadzirisa AMR pamatanho akasiyana-kubva pakukurumidza-ye-kutarisirwa kuongororwa kusvika kune yakadzama genetic kuongororwa-kuve nechokwadi chekupindira panguva uye kuderedza kupararira kwehutachiona hunopesana.
Kurwisa AMR nePrecision Diagnostics
PaMacro & Micro-Test, tinopa ekucheka-kumucheto diagnostic kits inogonesa varapi vehutano nekukurumidza, yakavimbika ruzivo, inogonesa kugadziriswa kwekurapa panguva uye kunoshanda kudzora hutachiona.
Sezvakasimbiswa mukati meWorld AMR Awareness Week, sarudzo dzedu nhasi dzicharatidza kugona kwedu kuchengetedza zvizvarwa zvazvino uye zvichauya kubva mukutyisidzirwa kweantimicrobial kuramba.
Batanidza muhondo yekurwisa antimicrobial kuramba — hupenyu hwese hwakaponeswa zvinhu.
For more information, please contact: marketing@mmtest.com
Nguva yekutumira: Nov-19-2025