Ongororo yePepa Rekutsvagisa Rekare
Respiratory Syncytial Virus (RSV) neHuman Metapneumovirus (HMPV) ndizvo zvinotapukira.utachiona hune hukama hwakasimba mukati mePneumoviridaemhuriizvo zvinowanzovhiringidzika muzviitiko zvehutachiona hwekufema hwevana. Kunyange zvazvo zviratidzo zvavo zvekiriniki zvichipindirana, data rekutarisa rinotarisirwa (2016–2020) kubva kuzvipatara zvinomwe zvevana zvekuUS—zvinosanganisira varwere 8,605—rinoratidza mutsauko wakakura muhuwandu hwavo huri panjodzi huru, kuoma kwechirwere, uye kurapwa kwekiriniki. Chidzidzo ichi chakashandisa dhizaini inoshanda, inotarisirwa ine kuunganidzwa kwakarongeka kweswab yemunopharyngeal uye kuyedzwa kwemavhairasi masere ekufema, zvichipa kuenzanisa kwekutanga kukuru, kwenyika chaiyo kwevanachiremba vevana. Nekuongorora mwero wekugara muchipatara, kubvumidzwa kuICU, kushandiswa kwemhepo inofefetera, uye kugara kwenguva refu muchipatara (≥mazuva matatu), inosimbisa hwaro hwakakosha hwe epidemiological isati yapindira yenguva yekudzivirira kutsva kweRSV (semuenzaniso, majekiseni emadzimai, ma antibodies emonoclonal anoshanda kwenguva refu) uye inogadzira hurongwa hwekuvandudzwa kwejekiseni reHMPV mune ramangwana.
Chinokosha 1: Mapurofayiri Akasiyana-siyana Ane Njodzi Yakawanda
-RSV inonyanya kubata vacheche vadiki:Avhareji yezera rekugara muchipatara yaive mwedzi minomwe chete, 29.2% yevarwere vakabvumirwa vari vacheche (mwedzi 0-2). RSV ndiyo inonyanya kukonzera kugara muchipatara muvacheche vari pasi pemwedzi mitanhatu, uye kuomarara kwacho kwakabatana nezera.
-HMPV inotarisa vana vakura nevaya vane zvimwe zvirwere:Avhareji yezera rekugara muchipatara yaive mwedzi gumi nemitanhatu, zvichikanganisa vana vanopfuura gore rimwe chete. Zvinonyanya kukosha ndezvokuti, kuwanda kwezvirwere (semuenzaniso, zvemwoyo, zvetsinga, zvekufema) kwaive kwakapetwa kaviri muvarwere veHMPV (26%) zvichienzaniswa nevarwere vane RSV (11%), zvichiratidza kuti vari panjodzi huru.
Mufananidzo 1. Kugoverwa kwezera kwekushanyira ED uye kuendeswa kuchipatarayakabatana neRSV kana HMPV
muvana vari pasi pemakore gumi nemasere.
Chinokosha 2: Kusiyanisa Mharidzo dzeKliniki
-RSV inoratidzwa nezviratidzo zvinoonekwa zvekufema kwepazasi:Inobatanidzwa zvakanyanya nechirwere chebronchiolitis (76.7% yevanhu vari muchipatara). Zviratidzo zvikuru zvinosanganisirakudhonzwa kwemadziro echipfuva (76.9% varwere vari muchipatara; 27.5% ED)uyetachypnea (91.8% varwere vari muchipatara; 69.8% ED), zvose zviri zviviri zvinowanzoitika zvakanyanya kupfuura muHMPV.
-HMPV ine njodzi yakakura yefivha uye pneumonia:Bayiko rakaonekwa mu35.6% yevarwere veHMPV vaiva muchipatara—kaviri huwandu hwevarwere veRSV.Fivha ndiyo yaive yakanyanya kupararira (83.6% yevarwere vairapwa; 81% ED)Kunyange zvazvo zviratidzo zvekufema zvakaita sekufema kwemweya uye tachypnea zvichiitika, kazhinji hazvinyanyi kuoma kupfuura muRSV.
Mufananidzo 2.Hunhu hwekuenzanisa uye klinikikosiyeRSV vs. HMPV muvana vari pasi pemakore gumi nemasere.
Pfupiso: RSVZvinowanzo kukonzera chirwere chakakomba muvacheche vadiki, chinoratidzwa nekunetseka kukuru kwekufema (kufemera, kudhonza) uye bronchiolitis.HMPVKazhinji inobata vana vakuru vane zvimwe zvirwere, inoratidzwa nefivha yakakura, ine njodzi yakakura yepneumonia, uye inowanzokonzera kuzvimba kwemuviri.
Chinokosha 3: Mapatani emwaka akakosha
-RSV ine nguva yekukurumidza uye inofungidzirwa:Basa rayo rakanyanya kuwanda, rinowanzo svika pakati peMbudzi naNdira, zvichiita kuti ive njodzi huru yehutachiona kuvacheche mumatsutso nemuchando.
-HMPV inozosvika pakakwirira gare gare nekusiyana kukuru:Mwaka wayo unosvika gare gare, kazhinji kusvika padanho repamusoroKurume naKubvumbi, uye inoratidza kusiyana kukuru kwegore negore uye kwenzvimbo, kazhinji kuchionekwa se "mafungu echipiri" mushure mekuderera kweRSV.
Mufananidzo 3.PCR yakanaka uye yakanangana nenzvimboemwero weRSV neHMPV pakati pevana vari pasi pemakore gumi nemasere vane kushanya kweED kunoenderana nehutachiona hwekufema (ARI) uye kuendeswa kuchipatara.
Kudzivirira uye Kutarisira: Hurongwa hweChiito Hunobva paUchapupu
-Kudzivirira RSV:Maitiro ekudzivirira ava kuwanikwa. Muna 2023, US FDA yakabvumidza mushonga wekudzivirira chirwere chemonoclonal (Nirsevimab) unoshanda kwenguva refu, unogona kudzivirira vacheche kwemwedzi mishanu yekutanga. Pamusoro pezvo, kubaiwa nhomba yeRSV neamai kunoendesa zvinobudirira ma antibodies ekudzivirira kuvacheche vachangozvarwa.
-Kudzivirira HMPV:Parizvino hapana mishonga yekudzivirira inotenderwa. Zvisinei, mishonga yakawanda inodiwa kuti ifukidzwe (semuenzaniso, mushonga weAstraZeneca weRSV/HMPV) iri kuyedzwa mukiriniki. Vabereki vanokurudzirwa kuti vagare vachiziva nezvezvichangobva kuitika kubva kumasangano ehutano hweveruzhinji.
Tsvaga Kurapwa Nekukurumidza Kana Uine "Zviratidzo Zvisina Kunaka" Izvi:
-Fivha muVacheche:Tembiricha ≥38°C (100.4°F) mucheche ari pasi pemwedzi mitatu yekuberekwa.
-Kukurumidza Kufema:Kufema kunodarika kufema makumi matanhatu paminiti kune vacheche vane mwedzi mumwe kusvika kumwedzi mishanu, kana kufema makumi mana paminiti kune vana vane makore 1-5, zvichiratidza kuti kufema kunogona kukanganiswa.
-Kuzara kweOkisijeni Yakaderera:Kuwanda kweokisijeni mumuviri (SpO₂) kunoderera pasi pe90%, chiratidzo chakakosha chekurwara kwakanyanya kwakaonekwa mu30% yeRSV uye 32.1% yezviitiko zveHMPV muchipatara muongororo iyi.
-Matambudziko Ekuneta kana Kudya:Kuneta kunoonekwa kana kudzikira kwemukaka neanopfuura chikamu chimwe muzvitatu mukati memaawa makumi maviri nemana, izvo zvinogona kukonzera kupera simba mumuviri.
Kunyange zvazvo zvakasiyana mu epidemiology uye mukurapa, kusiyanisa nemazvo pakati peRSV neHMPV panzvimbo yekurapwa kuchiri kuoma. Uyezve, njodzi yekiriniki inodarika mavhairasi maviri aya, nezvirwere zvakaita sefuruwenza A nezvimwe zvirwere zvemavhairasi nemabhakitiriya zvichityisidzira hutano hwevanhu panguva imwe chete. Saka kuongororwa kwechirwere nenguva kwakakosha kuti pave nerutsigiro rwakakodzera, kupatsanurwa kunoshanda, uye kugoverwa kwezviwanikwa zvine musoro.
Kuunza Kit yeAIO800 + 14-Pathogen Combined Detection Kit (Fluorescence PCR)(NMPA, CE, FDA, SFDA yakabvumidzwa)
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Iyi bvunzo yakazara yekufema inoongororamavhairasi nemabhakitiriyakubva pamuenzaniso mumwe chete, zvichibatsira vanopa hutano vari pamberi kuti vaite sarudzo dzekurapa dzine chivimbo, nenguva, uye dzakanangana.
Zvinhu Zvikuru zveSisitimu Zvakakosha kune Vatengi Vako
Kufamba Kwebasa Kwakazara Kwese
Nguva yekushanda nemaoko isingasviki maminetsi mashanu. Hapana chikonzero chevashandi vane hunyanzvi hwemamorekuru.
- Mhedzisiro Inokurumidza
Nguva yekudzoka kwemaminitsi makumi matatu inotsigira mamiriro ekurapa ekukurumidzira.
- 14Kuonekwa kwePathogen Multiplex
Kuzivikanwa panguva imwe chete kwe:
Mavhairasi:COVID-19,Influenza A & B,RSV,Adv,hMPV,Rhv,Parainfluenza marudzi I-IV,HBoV,EV,CoV
Mabhakitiriya:MP,Cpn,SP
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Zvinorerutsa kuchengetedza nekutakura, zvichibvisa kuvimba nezvinhu zvinochengetwa panguva yechando.
Sisitimu Yakasimba Yekudzivirira Kusvibiswa
Matanho ekudzivirira kusvibiswa ane zvidimbu gumi nerimwe anosanganisira kucheneswa kweUV, kusefa kweHEPA, uye closed-cartridge workflow, nezvimwewo.
Kuziva utachiona nekukurumidza uye kwakazara kwakakosha pakurapa kwezvirwere zvekufema kwevana. Sisitimu yeAIO800, ine multiplex PCR panel yayo inoshanda otomatiki kwemaminitsi makumi matatu, inopa mhinduro inoshanda yekutarisa mafambiro epamberi. Nekugonesa kuona RSV, HMPV, nezvimwe zvirwere zvakakosha, inopa simba vanachiremba kuti vasarudze kurapwa kwakanangana, vashandise mishonga inorwisa mabhakitiriya zvakanaka, uye vagadzire kudzora hutachiona zvinobudirira—pakupedzisira zvichivandudza kutarisirwa kwevarwere uye kushanda zvakanaka kwehutano.
#RSV #HMPV #Inokurumidza #Kuzivikanwa #Kufema #Chirwere Chinokonzera Utachiona #Muenzaniso-kupindura#Kuedza kweMacroMicro
Nguva yekutumira: Zvita-02-2025