MTHFR Gene Polymorphic Nucleic Acid
Product name
HWTS-GE004-MTHFR Gene Polymorphic Nucleic Acid Detection Kit (ARMS-PCR)
Epidemiology
Folic acid ivhitamini inonyungudika mumvura iyo yakakosha cofactor munzira dzemuviri dzemetabolism.Mumakore achangopfuura, nhamba huru yezvidzidzo zvakatsigira kuti, kuchinja kwefolate metabolizing enzyme gene MTHFR kunotungamirira kukushaya folic acid mumuviri, uye kukuvadzwa kunowanzoita folic acid kushomeka muvakuru kunogona kukonzera megaloblastic anemia, vascular. endothelial damage, etc. Kushaikwa kwefolic acid muvakadzi vane pamuviri hakugone kuzadzisa zvido zvavo uye nefetus, izvo zvinogona kukonzera neural tube defects, anencephaly, kufa, uye kupfupfudzika.Serum folate mazinga anokanganiswa ne5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms.Iyo 677C> T uye 1298A> C shanduko muMTHFR gene inokonzera kutendeuka kwealanine kuva valine uye glutamic acid, maererano, zvichiita kuti kuderedzwa kweMTHFR basa uye nokudaro kuderedza folic acid kushandiswa.
Channel
FAM | MTHFR C677T |
ROX | MTHFR A1298C |
VIC(HEX) | Kudzora mukati |
Technical Parameters
Storage | ≤-18℃ |
Sherufu-hupenyu | 12 mwedzi |
Type Type | Ichangobva kuunganidzwa EDTA anticoagulated ropa |
CV | ≤5.0% |
Ct | ≤38 |
LoD | 1.0ng/μL |
Zvishandiso Zvinoshanda: | Applied Biosystems 7500 Chaiyo-Nguva PCR Systems Applied Biosystems 7500 Fast Real-Time PCR Systems SLAN ®-96P Chaiyo-Nguva PCR Systems QuantStudio™ 5 Chaiyo-Nguva PCR Systems LightCycler®480 Chaiyo-Nguva PCR system LineGene 9600 Plus Chaiyo-Nguva PCR Detection System MA-6000 Chaiyo-Nguva Quantitative Thermal Cycler BioRad CFX96 Chaiyo-Nguva PCR System BioRad CFX Opus 96 Chaiyo-Nguva PCR System |
Kuyerera Kwebasa
Sarudzo 1
Zvinokurudzirwa kuburitsa reagents: Macro & Micro-Test Genomic DNA Kit (HWTS-3014-32, HWTS-3014-48, HWTS-3014-96) uye Macro & Micro-Test Automatic Nucleic Acid Extractor(HWTS-3006C, HWTS-300) .
Sarudzo 2
Zvinokurudzirwa zvekubvisa reagents: Ropa Genomic DNA Extraction Kit(YDP348, JCXB20210062) neTiangen Biotech(Beijing) Co.,Ltd.Ropa Genome Extraction Kit(A1120) naPromega.