Dengue NS1 Antigen, IgM/IgG Antibody Dual

Dengue fever chirwere chinotapukira chinokonzerwa nekurumwa kweumhutu hwechikadzi hune hutachiona hwedengue (DENV), uye chinotapurirana nekukurumidza, kuwanda kwacho kwakanyanya, kupararira kwacho kwakapararira, uye kufa kwakanyanya muzviitiko zvakakomba.^.

Vanhu vanosvika mamiriyoni mazana matatu nemakumi mapfumbamwe pasi rose vanobatwa nechirwere chedengue fever gore rega rega, uye vanhu mamiriyoni makumi mapfumbamwe nematanhatu vanobatwa nechirwere ichi munyika dzinopfuura zana nemakumi maviri, kunyanya muAfrica, America, Southeast Asia neWestern Pacific. Sezvo kudziya kwepasi rose kuri kuwedzera, chirwere chedengue fever chiri kupararira kunzvimbo dzine mamiriro ekunze anodziya uye anotonhora uye munzvimbo dzakakwirira, uye kuwanda kwezvirwere zve serotype kuri kuchinja. Mumakore achangopfuura, dambudziko rechirwere chedengue fever rakanyanya kuipa munzvimbo yeSouth Pacific, Africa, South America, kuchamhembe kweAsia neSoutheast Asia, uye rinoratidza kuwedzera kwakasiyana kwerudzi rwechirwere che serotype, nzvimbo iri kumusoro, mwaka, huwandu hwerufu uye huwandu hwezvirwere.

Ruzivo rwepamutemo rweWHO muna Nyamavhuvhu 2019 rwakaratidza kuti kwaive nevanhu vanosvika 200,000 vane dengue fever uye vanhu 958 vakafa muPhilippines. Malaysia yakanga yaunganidza vanhu vanodarika 85,000 vane dengue pakati paNyamavhuvhu 2019, ukuwo Vietnam yakanga yaunganidza vanhu 88,000. Zvichienzaniswa nenguva imwe chete muna 2018, nhamba iyi yakawedzera kanopfuura kaviri munyika dzese dziri mbiri. WHO yakaona dengue fever sedambudziko guru rehutano hwevanhu.

Chigadzirwa ichi ikiriti yekukurumidza, iripo uye chaiyo yekuona chirwere chedengue virus NS1 antigen uye IgM/IgG antibody. Chikiriti cheIgM chaiyo chinoratidza kuti pane hutachiona huchangobva kuitika, asi bvunzo yeIgM isina kunaka hairatidze kuti muviri hauna hutachiona. Zvakakoshawo kuona ma antibodies chaiwo eIgG ane hafu yenguva refu uye huwandu hwakanyanya hwehutachiona kuti usimbise chirwere chacho. Pamusoro pezvo, mushure mekunge muviri wabatwa nehutachiona, NS1 antigen inotanga kuonekwa, saka kuonekwa panguva imwe chete kwe NS1 antigen yedengue virus uye ma antibodies chaiwo eIgM neIgG zvinogona kunyatsoongorora mhinduro yemuviri kuhutachiona hwakati, uye iyi kiti yekuona antigen-antibody inogona kukurumidza kuongorora uye kuongorora pakutanga kwechirwere chedengue, hutachiona hwekutanga uye hutachiona hwechipiri kana hwakawanda hwedengue, kupfupisa nguva yekutarisa uye kuvandudza chiyero chekuonekwa.