Candida Albicans/Candida Tropicalis/Candida Glabrata Nucleic Acid Yakasanganiswa

Candida ndiyo yakakura yakajairwa fungal flora mumuviri wemunhu. Inowanikwa zvakanyanya mumhepo yekufema, digestive turakiti, urogenital turakiti uye dzimwe nhengo dzinotaurirana nekunze. Kazhinji, haisi pathogenic uye ndeye mukana wehutachiona hwehutachiona. Nekuda kwekushandiswa kwakawanda kwechirwere chekudzivirira uye huwandu hukuru hwema anti-spectrum antibiotics, pamwe nebundu radiotherapy, chemotherapy, invasive kurapwa, organ transplantation, iyo yakajairika flora haina kuenzana uye hutachiona hweCandida hunoitika mugenitourinary turakiti uye kufema turakiti. Candida albicans ndiyo inonyanya kuzivikanwa nekliniki, uye kune marudzi anopfuura gumi nematanhatu e-non-Candida albicans pathogenic bacteria, pakati peiyo C. tropicalis, C. glabrata, C. parapsilosis uye C. krusei yakawanda. Candida albicans iopportunistic pathogenic fungus inowanzo gara mudumbu remukati, muromo wemuromo, mukadzi uye mamwe mucous membranes uye ganda. Kana kudzivirira kwemuviri kukadzikira kana kuti microecology ikakanganiswa, inogona kuwanda muhuwandu uye kukonzera chirwere. Candida tropicalis iopportunistic pathogenic fungus inowanikwa zvakanyanya mumasikirwo uye mumuviri wemunhu. Kana kuramba kwemuviri kwadzikira, Candida tropicalis inogona kukonzera ganda, ukadzi, weti turakiti uye kunyangwe systemic hutachiona.

Mumakore achangopfuura, pakati pemarudzi eCandida akaparadzaniswa nevarwere vane candidiasis, Candida tropicalis inoonekwa seyokutanga kana yechipiri isiri Candida albicans (NCAC) muhuwandu hwekuzviparadzanisa, iyo inonyanya kuitika kune varwere vane leukemia, immunodeficiency, catheterization kwenguva refu, kana kurapwa nemishonga inorwisa mabhakitiriya. Huwandu hwehutachiona hweCandida tropicalis hunosiyana zvakanyanya nematunhu enzvimbo. Candida tropicalis utachiona huwandu hwevanhu hunosiyana zvakanyanya nenzvimbo dzenzvimbo. Mune dzimwe nyika, Candida tropicalis utachiona hunotopfuura Candida albicans. Izvo pathogenic zvinhu zvinosanganisira hyphae, cell surface hydrophobicity, uye biofilm kuumbwa. Candida glabrata inowanzoitika pathogenic fungus yevulvovaginal candidiasis (VVC). Chiyero chekoloni uye huwandu hwehutachiona hweCandida glabrata hunoenderana nezera rehuwandu. Iko colonization uye hutachiona hweCandida glabrata hahuna kunyanya kuwanda muvacheche nevana, uye huwandu hwekoloni uye huwandu hwehutachiona hweCandida glabrata hunowedzera zvakanyanya nezera. Kuwanda kweCandida glabrata kwakabatana nezvinhu zvakadai senzvimbo, makore, huwandu hwevanhu, uye kushandiswa kwefluconazole.