Aspirin Kuchengetedza Mushonga
Product name
HWTS-MG050-Aspirin Chengetedzo yeMedication Detection Kit (Fluorescence PCR)
Epidemiology
Aspirin, semushonga unoshanda we-anti-platelet aggregation drug, unoshandiswa zvakanyanya mukudzivirira uye kurapwa kwezvirwere zvemwoyo uye cerebrovascular.Chidzidzo chacho chinowana kuti vamwe varwere vakaonekwa kuti havakwanisi kuvharidzira zvinobudirira basa replatelet pasinei nekugara kwenguva refu-dose aspirin inoshandiswa, kureva, aspirin resistance (AR). Chiyero chinenge 50% -60%, uye kune misiyano yemarudzi iri pachena. Glycoprotein IIb/IIIa (GPI IIb/IIIa) inobata basa rinokosha muplatelet aggregation uye acute thrombosis panzvimbo dzekukuvara kwevascular. Zvidzidzo zvakaratidza kuti gene polymorphisms inoita basa rakakosha mukuramba aspirin, kunyanya kutarisa GPIIIa P1A1/A2, PEAR1 uye PTGS1 gene polymorphisms. GPIIa P1A2 ndiro jena guru rekuramba aspirin. Kuchinja-chinja kwejeni iri kunoshandura chimiro cheGPIIb/IIIa receptors, zvichikonzera kuyambuka-kubatana pakati peplatelet uye platelet aggregation. Chidzidzo chacho chakawana kuti kuwanda kweP1A2 alleles muvarwere vasingagamuchirwi neAspirin kwaive kwakakwirira kudarika kune varwere vane aspirin-sensitive, uye varwere vane P1A2 / A2 homozygous mutations vakanga vasina kushanda zvakanaka mushure mekutora aspirin. Varwere vane mutant P1A2 alleles vari kuita stenting vane subacute thrombotic chiitiko chiitiko chinopeta kashanu cheP1A1 homozygous mhuka dzesango, inoda madosi epamusoro easpirin kuti awane anticoagulant mhedzisiro. Iyo PEAR1 GG allele inopindura zvakanaka kune aspirin, uye varwere vane AA kana AG genotype vanotora aspirin (kana kusanganiswa neclopidogrel) mushure mekudyarwa kwe stent vane yakakwira myocardial infarction uye kufa. Iyo PTGS1 GG genotype ine njodzi yakakura yekupikisa aspirin (HR: 10) uye chiitiko chepamusoro chezviitiko zvemoyo (HR: 2.55). Iyo AG genotype ine njodzi iri pakati nepakati, uye kunyatsotarisisa kunofanirwa kubhadharwa kune mhedzisiro yeAspirin kurapwa. Iyo AA genotype inonyanya kunetseka kune aspirin, uye chiitiko chezviitiko zvemoyo chinenge chakaderera. Mhedzisiro yekuonekwa kwechigadzirwa ichi inongomiririra mhedzisiro yemunhu PEAR1, PTGS1, uye GPIIIa majini.
Technical Parameters
| Storage | ≤-18℃ |
| Sherufu-hupenyu | 12 mwedzi |
| Type Type | Huro swab |
| CV | ≤5.0% |
| LoD | 1.0ng/μL |
| Zvishandiso Zvishandiso | Inoshanda kutaipa I yekuona reagent: Applied Biosystems 7500 Chaiyo-Nguva PCR Systems, Vadivelu Comedy QuantStudio®5 Chaiyo-Nguva PCR Systems, SLAN-96P Chaiyo-Nguva PCR Systems (Hongshi Medical Technology Co., Ltd.), LineGene 9600 Plus Chaiyo-Nguva PCR Detection Systems (FQD-96A, Hangzhou Bioer tekinoroji), MA-6000 Chaiyo-Nguva Quantitative Thermal Cycler (Suzhou Molarray Co., Ltd.), BioRad CFX96 Chaiyo-Nguva PCR System, BioRad CFX Opus 96 Chaiyo-Nguva PCR System. Inoshanda kune Type II yekuona reagent: EudemonTMAIO800 (HWTS-EQ007) naJiangsu Macro & Micro-Test Med-Tech Co., Ltd. |
Kuyerera Kwebasa
Micro-Test Automatic Nucleic Acid Extractor (HWTS-3006C, HWTS-3006B)) by Jiangsu Macro & Micro-Test Med-Tech Co., Ltd.
Iyo yakabviswa sampuli vhoriyamu i200μL uye yakakurudzirwa elution vhoriyamu i100μL.
